Altering substrate availability profoundly affects left ventricular function in the normal heart
نویسندگان
چکیده
منابع مشابه
Altering substrate availability profoundly affects left ventricular function in the normal heart
Background Although altered cardiac substrate selection has been proposed to be the cause for many cardiac diseases and has been suggested to be a target to improve cardiac function, the effect of modulating substrate availability on global LV function in the normal heart has not been investigated. Our aim was to use CMR to investigate global cardiac function and strain before and after modulat...
متن کاملNormal left ventricular function.
The Starling relationship in the normal human ventricle may be different than usually portrayed. In normal, resting, supine man the ventricular function curve is at its peak at a left ventricular end-diastolic pressure of approximately 10 mm Hg. Below this point is a strong direct relation between filling pressure and stroke work, while at higher filling pressures, a plateau occurs. Limitation ...
متن کاملLEFT VENTRICULAR DIASTOLIC ABNORMALITIES IN β-THALASSEMIA MAJOR WITH NORMAL SYSTOLIC FUNCTION
In order to identify left ventricular diastolic function in patients with betathalassemia major and normal systolic function by noninvasive M-mode and Doppler echocardiography, an analytic study was designed in a university hospital in Sari. We have studied 44 patients (23 men and 21 women), mean age 15.48±2.16 (range 12 to 20) and 43 age and sex matched control subjects. Peak flow velocit...
متن کاملLeft Ventricular Function in the Canine Heart
SIJMMARY We quantitatively analyzed the effect of graded left anterior descending and septal coronary flow (LAD + septal flow) reduction on left ventricular function with a left ventricular end-diastolic pressure (LVEDP) of 6 mm Hg and 12 mm Hg. We used an isolated, ejecting, canine heart preparation (n = 8), the coronary flow of which could be controlled independently of the aortic pressure. W...
متن کاملLeft ventricular-arterial coupling relations in the normal human heart.
This investigation was undertaken to assess left ventricular-arterial coupling relations in the normal human heart under varying loading conditions and inotropic states and thereby to establish whether the working point of the normal human heart is at optimal output or mechanical efficiency under basal hemodynamic conditions. In 22 patients with an atypical chest pain syndrome who had normal co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance
سال: 2016
ISSN: 1532-429X
DOI: 10.1186/1532-429x-18-s1-q32